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Recrudescence is the recurrence of an undesirable condition. In medicine, it is usually defined as the recurrence of symptoms after a period of remission or quiescence,[1][2][3] in which sense it can sometimes be synonymous with relapse. In a narrower sense, it can also be such a recurrence with higher severity than before the remission.[3] "Relapse" conventionally has a specific (albeit somewhat illogical) meaning when used in relation to malaria (see below).