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Pertussis vaccine

Pertussis vaccine
Pertussis vaccination is often administered via a combined DPT vaccine or, as shown here, a DTaP-IPV vaccine
Vaccine description
TargetWhooping cough
Vaccine typeInactivated or subunit
Clinical data
MedlinePlusa682198
ATC code
Legal status
Legal status
  • US: ℞-only
  • In general: ℞ (Prescription only)
Identifiers
DrugBank
ChemSpider
  • none
UNII
 ☒NcheckY (what is this?)  (verify)

Pertussis vaccine is a vaccine that protects against whooping cough (pertussis).[1][2] There are two main types: whole-cell vaccines and acellular vaccines.[1][2] The whole-cell vaccine is about 78% effective while the acellular vaccine is 71–85% effective.[1][3] The effectiveness of the vaccines appears to decrease by between 2 and 10% per year after vaccination with a more rapid decrease with the acellular vaccines.[1] The vaccine is only available in combination with tetanus and diphtheria vaccines.[1] Pertussis vaccine is estimated to have saved over 500,000 lives in 2002.[4]

  1. ^ a b c d e "Pertussis vaccines: WHO position paper – September 2015" (PDF). Relevé Épidémiologique Hebdomadaire. 90 (35): 433–458. August 2015. PMID 26320265. Archived from the original (PDF) on 4 March 2016.
  2. ^ a b "The Immunological Basis for Immunization Series: Pertussis Vaccines". World Health Organization. Archived from the original on 23 March 2018. Retrieved 22 November 2017.
  3. ^ Zhang L, Prietsch SO, Axelsson I, Halperin SA (September 2014). "Acellular vaccines for preventing whooping cough in children". The Cochrane Database of Systematic Reviews. 2014 (9): CD001478. doi:10.1002/14651858.CD001478.pub6. PMC 9722541. PMID 25228233.
  4. ^ "Annex 6 whole cell pertussis" (PDF). World Health Organization. Archived (PDF) from the original on 24 March 2012. Retrieved 5 June 2011.

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