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Ethanolamine
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| Names | |
|---|---|
| Preferred IUPAC name
2-Aminoethan-1-ol[1] | |
Other names
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.004.986 |
| EC Number |
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| KEGG | |
PubChem CID
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| RTECS number |
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C2H7NO | |
| Molar mass | 61.084 g·mol−1 |
| Appearance | Viscous colourless liquid |
| Odor | Unpleasant ammonia-like odour |
| Density | 1.0117 g/cm3 |
| Melting point | 10.3 °C (50.5 °F; 283.4 K) |
| Boiling point | 170 °C (338 °F; 443 K) |
| Miscible | |
| Vapor pressure | 64 Pa (20 °C)[2] |
| Acidity (pKa) | 9.50[3] |
Refractive index (nD)
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1.4539 (20 °C)[4] |
| Hazards | |
| GHS labelling: | |
 
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| Danger | |
| H302, H312, H314, H332, H335, H412[5] | |
| P261, P273, P303+P361+P353, P305+P351+P338[5] | |
| NFPA 704 (fire diamond) | |
| Flash point | 85 °C (185 °F; 358 K) (closed cup) |
| 410 °C (770 °F; 683 K) | |
| Explosive limits | 5.5–17% |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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| NIOSH (US health exposure limits): | |
PEL (Permissible)
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TWA: 3 ppm (6 mg/m3)[6] |
REL (Recommended)
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IDLH (Immediate danger)
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30 ppm[6] |
| Safety data sheet (SDS) | Sigma[5] |
| Related compounds | |
Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Ethanolamine (2-aminoethanol, monoethanolamine, ETA, or MEA) is a naturally occurring organic chemical compound with the formula HOCH
2CH
2NH
2 or C
2H
7NO.[8] The molecule is bifunctional, containing both a primary amine and a primary alcohol. Ethanolamine is a colorless, viscous liquid with an odor reminiscent of ammonia.[9]
Ethanolamine is commonly called monoethanolamine or MEA in order to be distinguished from diethanolamine (DEA) and triethanolamine (TEOA). The ethanolamines comprise a group of amino alcohols. A class of antihistamines is identified as ethanolamines, which includes carbinoxamine, clemastine, dimenhydrinate, chlorphenoxamine, diphenhydramine and doxylamine.[10]
- ^ a b Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. pp. 649, 717. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
For example, the name 'ethanolamine', which is still widely used, is badly constructed because of the presence of two suffixes; it is not an alternative to the preferred IUPAC name, '2-aminoethan-1-ol'.
- ^ "Ethanolamine MSDS" (PDF). Acros Organics. Archived from the original (PDF) on 2011-07-15.
- ^ Hall, H.K. (1957). "Correlation of the Base Strengths of Amines". J. Am. Chem. Soc. 79 (20): 5441–4. doi:10.1021/ja01577a030.
- ^ Reitmeier, R.E.; Sivertz, V.; Tartar, H.V. (1940). "Some Properties of Monoethanolamine and its Aqueous Solutions". Journal of the American Chemical Society. 62 (8): 1943–44. doi:10.1021/ja01865a009.
- ^ a b c Sigma-Aldrich Co., Ethanolamine. Retrieved on 2018-05-24.
- ^ a b c NIOSH Pocket Guide to Chemical Hazards. "#0256". National Institute for Occupational Safety and Health (NIOSH).
- ^ "Ethanolamine". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
- ^ "National Library of Medicine. PubChem. Ethanolomine". NIH, National Library of Medicine. Retrieved September 5, 2021.
- ^ Martin Ernst; Johann-Peter Melder; Franz Ingo Berger; Christian Koch (2022). "Ethanolamines and Propanolamines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a10_001.pub2. ISBN 978-3527306732.
- ^ Cough, Cold, and Allergy Preparation Toxicity at eMedicine
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